The neuronal cytoskeleton
نویسندگان
چکیده
منابع مشابه
Building the Neuronal Microtubule Cytoskeleton
Microtubules are one of the major cytoskeletal components of neurons, essential for many fundamental cellular and developmental processes, such as neuronal migration, polarity, and differentiation. Microtubules have been regarded as critical structures for stable neuronal morphology because they serve as tracks for long-distance transport, provide dynamic and mechanical functions, and control l...
متن کاملRegional differences in the neuronal cytoskeleton.
Regional differences in the neuronal cytoskeleton were investigated in the giant neurons of Aplysia. Using SDS-PAGE, we have compared the proteins which comprise the cytoskeletons of cell bodies and axons. Separate populations of cell bodies and axons were collected and the proteins stained by the Coomassie brilliant blue method. Individual identified cell bodies, with long segments of their ax...
متن کاملNeuronal RNA localization and the cytoskeleton.
The ability of a neuronal process to grow and be properly directed depends upon the growth cone, whose shape and sensory capabilities are influenced by dynamic cytoskeletal filament systems. Microfilaments, which are composed of actin, can rapidly form bundles that affect filopodial protrusions, growth cone motility and process growth. An important area of basic research is to understand how th...
متن کاملMolecular mechanisms for organizing the neuronal cytoskeleton.
Neurofilaments and microtubules are important components of the neuronal cytoskeleton. In axons or dendrites, these filaments are aligned in parallel arrays, and separated from one another by nonrandom distances. This distinctive organization has been attributed to cross bridges formed by NF side arms or microtubule-associated proteins. We recently proposed a polymer-brush-based mechanism for r...
متن کاملDynamic imaging of neuronal cytoskeleton.
Growth cones are the motile tips of growing axons. During development growth cones guide axons along specific pathways to appropriate targets by extending toward or retracting away from attractive or inhibitory guidance cues in their environment. Growth cone motility as well as extension, retraction, and turning behaviors are directed by the neuronal cytoskeleton, principally actin filaments an...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1992
ISSN: 0014-5793
DOI: 10.1016/0014-5793(92)81156-g